The recommended starting dose for adults is 2.5 mg of rosuvastatin administered once daily. However, for patients requiring prompt lowering of LDL-cholesterol levels, administration of this drug may be started at a dose of 5 mg. The dose may be adjusted appropriately according to patient’s age and symptoms, and may be gradually increased to 10 mg if an inadequately decreased LDL-cholesterol level is observed at 4 weeks after the start of treatment or after the dose increase. The dose may be further increased up to 20 mg per day for patients with severe conditions such as patients with familial hypercholesterolemia whose LDL-cholesterol levels are not sufficiently lowered by administration of this product at a dose of 10 mg.